First-year medical student
Andrew Razzano was very close to his grandfather, Frank Razzano.
After developing Type 2 diabetes, the elder Razzano, a World War II
veteran, passed away from heart-related complications resulting from
his diabetes.
The death of his grandfather set
the younger Razzano on the path of medical research and sparked his
dream of becoming a doctor. As an undergraduate majoring in
biological sciences at Ohio University, he jumped at the chance to
work for John Kopchick, Ph.D., a principal investigator at
the Edison Biotechnology Institute. Kopchick pioneered the discovery
of the drug Somavert, a growth hormone receptor antagonist that
eventually may also prove effective against diabetes. He and other
Edison principal investigators are currently engaged in researching
cures for diabetes.
Because of that chance, in 2004,
near the end of his junior year, Razzano became an AMVETS scholar —
as Kopchick refers to the undergraduate research position, says
Razzano. AMVETS scholars are funded by AMVETS, one of America’s
foremost veterans service and are made possible by the
organization’s Diabetes Institute Training Award, which AMVETS began
three years ago. AMVETS — including Athens Post 76, Logan Post 1776,
and national and district posts — has raised more than $50,000 to
fund undergraduate research at Edison. Razzano was eligible for the
award because his grandfather and others in his family served in the
military.
At first, says Razzano, he had to
“learn lab protocols and read a lot of research-related articles.
Then I was able to start doing DNA isolation, worked on an aging
study and eventually designed my own study.
“The research I did at Edison dealt
with the vascular inflammation associated with Type 2 diabetes. It
truly meant a lot to me because diabetes has affected my family,
like so many others. Unlike most of those affected, I have had the
opportunity to make a difference in this area,” Razzano says. He
graduated with a bachelor in biological science/pre-medicine. He
also spent a summer in OU-COM’s undergraduate research program.
At Kopchick’s lab, he says, “You
are treated as a lab technician. You are involved in the weekly
meetings. You have to be on your toes. John expects a lot from us.”
And that’s good, says Razzano.
“It’s great because you are working
in a business-oriented, drug-producing laboratory. You get to see
firsthand the process from beginning to end — from the inception of
the approach to envisioning the end goal.”
Bill Butcher, a member of local
Post 76, says AMVETS saw the need to assist this community, one
affected by the prevalence of diabetes, by supporting diabetes
research.
“This was a major push for our
organization,” says Butcher.
Butcher discussed with Kopchick, a
personal friend, how AMVETS could best help diabetes research
efforts underway at Edison. After the details were worked out, the
Diabetes Institute Training Award was founded.
The National AMVETS has donated
$15,000 each year for the Diabetes Institute Training Award.
Locally, AMVETS posts have donated $2,000 each year to fund the
award.
“For Bill and AMVETS to fund this
program for undergraduates says a lot about the commitment they have
to help our community and support students who are seeking to make a
difference,” says Kopchick.
The award program is open to Ohio
undergraduates and was designed to give students a peek into the
research side of medicine, Kopchick says.
“They not only learn how to do
diabetes research, in the process they make new discoveries. It’s
our hope that some of these discoveries will lead to new
therapeutics for the treatment of diabetic patients. It’s a very
good research-oriented program.”
Two other Ohio graduates have also
been AMVETS scholars, Megan Buchholtz and Stephanie Keeton.
Currently there are four students training at Edison through the
AMVETS program: Andrew Dittenhoffer, Josh Harbert, Kerri Bauske and
Frank Hartge, an Iraqi war veteran.
Like Razzano, for students to
qualify for the award they must have a veteran in the family or be
one themselves. The award helps pay their salaries as well as for
research supplies and travel expenses. In 2005, Razzano traveled
with fellow AMVETS scholars to present at the Annual Endocrinology
Society Meeting in San Diego.
He says the experience he had at
Edison was amazing.
“I received top notch research
experience and participated in a great work environment,” he says.
“To be part of a research effort that has produced numerous
intellectual patents and has a drug on the market right now —
Somavert — allowed me to see how much work goes into researching
diseases. I saw how researchers can target a disorder and produce a
drug to fix it.
“All the great experiences I have
had would not have been possible with out the support and
encouragement of AMVETS. The organization took a great interest not
only in my research but also in me as a person.
“AMVETS wanted to know what we were
doing — they would come by the laboratory and talk with us about
what we did. I’ve also been to the post a few times. They would
honor us at post meetings and would give us a chance to talk about
our research. It was a great opportunity.”
“It’s wonderful,” says Kopchick,
“to see the look on students’ faces when I tell them that they are
the recipients of the AMVETS Diabetes Institute Training Award.”