Treating depression in rural adults with
HIV/AIDS
Tim Heckman receives $1.6 million NIH grant to
test telepsychiatry program
By Anita Martin
Friday, Dec. 18, 2009
Living in a small town, you can learn a lot
about your neighbors; you see them at the
grocery store, the pharmacy, the doctor’s
office. The lack of anonymity helps explain why
HIV-infected rural residents are less likely to
visit health professionals, says Tim Heckman,
Ph.D., and the resulting lack of care takes
a toll not only on their physical health, but
also on their psychological and emotional
well-being.
According to Heckman, HIV-infected people in
rural areas are 1.3 times more likely to be
diagnosed with depression than those in urban
areas. “People with HIV living in rural areas
are more isolated, emotionally and physically,”
he says. “There’s often a greater stigma
associated with HIV and AIDs and reduced access
to care.”
To help combat depression among HIV-infected
rural residents, Heckman, OU-HCOM professor of
geriatric medicine, is leading a nationwide
study to test whether telephone-administered
psychotherapy can reduce depression in this
group.
“Telepsychiatry provides access to mental health
services for people with geographical or
physical limitations, and it offers greater
confidentiality for people in small towns who
may experience less privacy and greater stigma,”
he says.
To support his efforts, the National Institutes
of Health (NIH) recently awarded Heckman a
four-year, $1,630,785 grant. In this first year,
NIH will provide $388,382 to help launch the
program. The first year of the project will
involve recruiting rural persons with HIV/AIDS
and screening them for major depressive
disorder, as well as training clinical
psychologists in telephone-administered
interpersonal psychotherapy (IPT).
“IPT is a short-term psychotherapy that focuses
on interpersonal relationships, which often
cause or contribute to one’s depression,” says
Heckman, explaining that interpersonal dilemmas
that can lead to depression include
bereavements; “role transitions,” which can
range from divorce to job loss to being
diagnosed with a serious illness; interpersonal
disputes; and “interpersonal deficits” defined
as ongoing difficulties in forming and
maintaining close relationships.
Heckman’s study will recruit 90 HIV-infected
rural persons diagnosed with major depressive
disorder who will receive nine sessions of
one-on-one telephone-administered ITP. The
participants will also provide weekly data on
their depressive symptoms for 41 weeks, before,
during and following the intervention. Ninety
additional HIV-infected rural persons with
depression will also be recruited into the study
but will not receive any active treatment from
the study team.
Although this study is focused primarily on
depression, studies have correlated depression
in HIV-infected individuals with reduced
adherence to HAART (highly active antiretroviral
therapy), increased high HIV-transmission risk
behaviors and shorter survival periods.
“This study is about reducing depression, but
secondarily, we hope to see greater HAART
adherence and Heckman says.
To develop the program, Heckman is collaborating
with professionals at Northwestern University,
Indiana University and Columbia University,
including two of the founders of IPT, John
Markowitz, M.D., and Myrna Weissman, Ph.D. To
conduct the telephone psychotherapy, Heckman
plans to work with clinical psychologists
primarily from Southeastern Ohio.
In addition to this grant, Heckman recently
received $371,573 from the NIH to complete a
related four-year project, “Telephone-delivered
coping improvement intervention for HIV-infected
older adults.” To read about this study, which
addresses the psychological needs of
HIV-infected adults 50 years of age and older,
go to
www.oucom.ohiou.edu/OUM/Winter-09/AgingOfAids.htm.