We have developed small cationic antimicrobial peptides, based on a linear amphipathic β-sheet motif, that possess high antimicrobial potency combined with low mammalian cell toxicity since they induce lysis in target membranes in a highly selective manner.

These peptides have potential as topical agents for the treatment of antibiotic-resistant bacterial infections.

Jack Blazyk, Ph.D.
Emeritus Professor of Biochemistry

blazyk@ohio.edu


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Last updated: 01/20/2015