Yang V. Li, M.D., Ph.D.
Associate Professor of Neuroscience
Department of Biomedical Sciences
li@oucom.ohiou.edu
liy1@ohio.edu
346 Irvine Hall
740-593-2384
 
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DEPT. OF BIOMEDICAL SCIENCES
DEPT. OF BIOLOGICAL SCIENCES
GRADUATE STUDIES IN BIOLOGY
MOLECULAR & CELLULAR BIOLOGY PROGRAM

Selected Publications

Christian J. Stork & Yang V. Li, Rising zinc: a significant cause of ischemic neuronal death in the CA1 region of rat hippocampus. J Cereb Blood Flow Metab. 2009 Jun 3. [Epub ahead of print]
 

Joshua Ketterman & Yang V. Li, Presynaptic evidence for zinc release at the mossy fiber synapse of rat hippocampus. J Neuroscience Research. 2008 Feb 1;86(2):422-334
 

Chinthasagar Bastian & Yang V. Li, Fluorescence imaging study of extracellular zinc at the hippocampal mossy fiber synapse. Neuroscience Letter. 2007 May 29;419(2):119-24. Epub 2007 May 4.
 

Christian J. Stork & Yang V. Li, Intracellular zinc elevation measured with a "calcium-specific" indicator during ischemia and reperfusion in rat hippocampus: a question on calcium overload.  The Journal of Neuroscience.  2006 Oct 11;26(41):10430-7.

 

Jennifer L. Martin, Christian J. Stork, & Yang V. Li, Determining zinc with commonly used calcium and zinc fluorescent indicators, a question on calcium signals. Cell Calcium. 2006 Oct;40(4):393-402. Epub 2006 Jun 9.

 

Caleb O. Molokwu & Yang V. Li, Zinc homeostasis and bone mineral density. Ohio Research and Clinical Review. Fall 2006;15:7-15. COVER

 

Christian J. Stork & Yang V. Li, Measuring cell viability with membrane impermeable zinc fluorescent indicator. Journal of Neuroscience Methods. 2006 Sep 15;155(2):180-6. Epub 2006 Feb 8.

 

Guo Wei, Christopher J. Hough, Yang Li, John M. Sarvey (2004) Characterization of extracellular accumulation of Zn2+ during ischemia and reperfusion of hippocampus slices in rat. Neuroscience. 125(4):867-77.

Yang V. Li, Christopher J. Hough & John M. Sarvey (2003) Do we need zinc to think? Science STKE, pe19 (review).

Yang Li, Christopher J. Hough, Christopher J. Frederickson & John M. Sarvey (2001) Induction of Mossy Fiber-CA3 LTP Requires Translocation of Synaptically Released Zn2+, Journal of Neuroscience. Oct 15;21(20):8015-25.

Yang Li, Christopher J. Hough, Sang Wan Suh, John M. Sarvey & Christopher J. Frederickson (2001) Rapid Translocation of Zn2+ from Nerve Terminals into Postsynaptic Hippocampal Neurons Following Physiological Stimulation, Journal of Neurophysiology. Nov;86(5):2597-604.PDF full text

Yang Li, Lynne A. Holtzclaw, James T. Russell, (2001) Müller cell Ca2+ waves evoked by purinergic agonists in freshly isolated rat retinal slices. Journal of Neurophysiology, 85(2):986-994.

Yang Li, M. Steven Evans, Carl L. Faingold, (1999) Synaptic response patterns of neurons in the cortex of rat inferior colliculus. Hearing Research. Nov;137(1-2):15-28.

Yang Li, M. Steven Evans, Carl L. Faingold, (1998) A comparison of electrophysiological properties in three subnuclei of rat inferior colliculus in vitro. Hearing Research. Jul;121(1-2):1-10.

Yang Li, M. Steven Evans, Carl L. Faingold, (1994) Inferior colliculus neuronal membrane and synaptic properties in genetically epilepsy-prone rats. Brain Research, 660:232-240.

 

          

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Recent Abstracts & Posters (2004-2007)

C. Bastian, Y.V. Li. Zinc in the Recurrent Mossy Fiber Pathway of the Epileptic Brain. Program No 3.044. The 61st Annual Meeting of American Epilepsy Society. Philadelphia, PA. 2007

D. Tian, Y. V. Li. Inhibitory action of synaptically released zinc in the adult hippocampal mossy fiber CA3 synapse. Program No. 358.2. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online

C.J. Stork, Y.V. Li. Evidence for rising zinc as the primary cause of ischemic neuronal death, not calcium  Program No. 898.10. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online

J. K. Ketterman, Y. V. Li, Direct evidence for vesicular zn2+ release: localization, kinetics, and pharmacology. Program No. 358.3. 2007 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2007. Online

C.J. Stork, S. Wu, Y.V. Li., Intracellular Zinc Elevation Measured with a “Calcium-Specific” indicator: A Question on Calcium Signals. 2007 Experimental Biology meeting abstracts [on CD-ROM], Abstract #945.13

C.J. Stork, Y.V. Li., Prevention of cellular damage during OGD/reperfusion, 6th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 12, 2007 (the 1st Place Award Poster)

Caleb O. Molokwu and Yang V. Li. Effect of a Zinc Chelator and 17ß-Estradiol Administration on Bone Mineral Density of Ovariectomized Rats. 6th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 12, 2007

C.B. Arthur,  Y.V. Li. The Effects of Zinc Chelators on Hemostasis and Blood Clot Lysis, 6th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 12, 2007 (the 2nd Place Award Poster)

S. Simpson, Y.V. Li. A means of identifying the neurooprotective mechanisms of zinc chelation, 6th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 12, 2007

J. K. Ketterman, Y. V. Li. Characterization of presynaptic Zn2+ kinetics at the MF-->CA3 synapse by use of a novel fluorescent model. Program No. 36.4/C59. 2006 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2006. Georgia World Congress Center.

C. J. Stork, Y. V. Li. Exploiting zinc liberation during cell death as a means for assessing cellular viability. Program No. 679.3/MM94. 2006 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2006. Georgia World Congress Center.

Y. V. Li, C. J. Stork. Fluorescent calcium indicators and elevated zinc during ischemia and reperfusion. Program No. 710.9. 2006 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2006. Georgia World Congress Center.

J. Ketterman, Y.V. Li.  A New Model for Observing Presynaptic Zn2+ Kinetics in the Mammalian Hippocampus. 5th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 4, 2006

C.J. Stork, Y.V. Li.  Zinc and Ischemic Stroke, 5th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 4, 2006 (the 1st Place Award Poster)

M.Y. Braasch, Y.V. Li.  A Model of Learning: LTP in the CA1 Region of the Hippocampus, 5th Annual Student Research and Creative Activity Fair, Convocation Center. Ohio University. May 4, 2006 (the 2ne Place Award Poster)

C.J. Stork, Y.V. Li. Evidence of Intracellular Zinc Elevation During Ischemia and Reperfusion In Rat Hippocampus Slices, A Question On Calcium Overload Program No. 219.8. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

J.L. Martin, Y.V. Li. Determining Zinc with Commonly Used Fluorescent Calcium and Zinc Indicators in Physiological Medium Program No. 219.10. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

C. Bastian, Y.V. Li. A Comparative Study of Actions of Three Cell Impermeable Fluorescent Indicators on Synaptically Released Zinc Program No. 731.17. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. 

C. Molokwu, and Y.V. Li (2005) Progress in Zinc Homeostasis with Bone Mineral Density. Research Day, Ohio University College of Osteopathic Medicine, Irvine Hall. 

J.L. Martin, Y.V. Li (2005) Calcium Fluorescent Indicators are Capable of Detecting Zinc in Physiological Conditions. Ohio University Student Science Fair, Convocation Center. (The 2nd place award wining poster)

C.J. Stork, Y.V. Li (2005) Zinc Overload in Ischemia and Reperfusion. Ohio University Student Science Fair, Convocation Center.

Yang V Li. (2004) Detect Zn2+ with Selective Ca2+ or Zn2+ Fluorescent Indicators in Ischemia and Epilepsy. Society for Neuroscience annual meeting, San Diego.

Y. Ding, &  Y. Li., (2004) Preliminary Study of Zinc Release from Recurrent Mossy Fibers in Pilocarpine Models of Epilepsy. Research Day, OUCOM.

 

J. Martin, Y. Ding, & Y. Li., (2004) Detection of Zinc with Calcium Fluorescent Indicators--Characterization of Fluorescent Indicators for Calcium and Zinc in vitro. Research Day, OUCOM.

 

C. Stork, Y. Ding, & Y. Li., (2004) Preliminary Study of Zinc, not Calcium, Elevation in Rat Hippocampal Slices under Ischemia and Reperfusion. Research Day, OUCOM.

  

E. Gesing, C. Stork, & Y. Li., (2004) Zinc precipitations in Artificial Cerebral Spinal Fluid. Research Day, OUCOM. Irvine Hall, Ohio University.

Yang V Li, (2004) Detect Released Zinc with Fluorescent Probes. Zinc Signals 2004-annual international conference. Aarhus, Denmark. 

   
     
  Ohio University
College of Osteopathic Medicine
Irvine Hall, Athens, Ohio 45701
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Last updated: 10/16/2009