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Physician researchers at the Ohio University College of Osteopathic Medicine are recruiting type 2 diabetes patients for a clinical trial to look at the benefits of short-term intensive insulin therapy on long-term diabetes management.

Diabetes is a chronic disease of the pancreatic beta cells, which produce insulin to manage blood sugar, or glucose. In type 2 diabetes, the pancreas progressively loses its ability to produce insulin, leading to high blood glucose levels and possible beta cell failure and cell death.

"Recent studies have shown that intensive insulin at the onset of type 2 diabetes can prevent pancreatic cell failure early on, leading to long-term control of glucose and reducing the need for expensive treatments down the road," said Jay Shubrook, D.O.

In a previous case series, Shubrook administered 12 weeks of intensive insulin therapy to newly diagnosed diabetes patients. Since then, the patients have had stable glucose levels for up to two and a half years – with no medication or insulin. Normally, Shubrook said, a type 2 diabetes patient starts with one medication to control glucose levels and has to increase his or her medications over time to keep glucose in check.

The physician researchers are looking for adults who have been diagnosed with type 2 diabetes within the past six months and who do not have congestive heart failure, renal failure, or nephrotic syndrome.
Participants will receive:

• Free medical visits

• Free laboratory testing

• Free medication and testing supplies for one year

• Payments for each visit they attend

• The opportunity to gain control of their diabetes