Grijalva
will receive a three-year $201,839 NIH award this month
for his grant proposal, “Characterization of
Trypanosoma cruzi in Southern Ecuador.”
Trypanosoma
cruzi is the organism that causes Chagas, a
parasitic human disease found mostly in Latin America.
The disease is spread through the blood-sucking insect
triatomines, also called “kissing bugs,” which live
between northern Argentina and the southern United
States.
According to
Grijalva, little is known about Chagas—even though an
estimated 10 million people are infected with this
potentially fatal disease, and about 200 million are at
risk. Even Grijalva—a native Ecuadorian—had not heard
about the disease until he came to OU-HCOM as a graduate
student and began collaborating with Edwin Rowland,
Ph.D., associate professor and chair of
microbiology, on his Chagas research.
Grijalva hopes
to shed some light on Chagas by tracking the movement of
the disease throughout the region of Loja, Ecuador. He
will take samples from the triatomine bugs and from
people and other mammals—rodents, dogs and cats—that
have been infected with Chagas. According to Grijalva,
understanding the transmission of Chagas will help
inform country-wide Chagas disease control programs in
Ecuador.
“This research
allows us to strengthen current Chagas control
initiatives, which will benefit millions of people,”
Grijalva said. “It also provides an ideal environment
for training of students and faculty from Ecuadorian
institutes and Ohio University.”
This summer
Grijalva will lead an interdisciplinary research team of
25 students—medical, undergraduate and graduate—to
Ecuador. About half will be Ohio University students,
and the other half hail from universities across the
country. They will work together with Ecuadorian
students and faculty, the Ecuador Ministry of Health,
and both government and non-government organizations.